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Article

Is it important to decipher the heterogeneity of "normal karyotype AML"?

Best practice & research. Clinical haematology - 1 Mar 2008

Nimer Stephen D

Abstract excerpt

Almost half of adult acute myelogenous leukemia (AML) is normal cytogenetically, and this subgroup shows a remarkable heterogeneity of genetic mutations at the molecular level and an intermediate response to therapy. The finding of recurrent cytogenetic abnormalities has influenced, in a primary...

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Topics

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Share to Chromosome Aberrations
Share to Drug Resistance, Neoplasm
Share to Hematopoietic Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Karyotyping

Share to Leukemia, Myeloid, Acute

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Share to Neoplasm, Residual

Share to Tandem Repeat Sequences

Source

Open in PubMed Open full text

Identifiers

PMID: 18342811
DOI: 10.1016/j.beha.2007.11.010
PMCID: PMC2654590

Genes

ERG
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18342811-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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