Article
Molecular prognostic factors in cytogenetically normal acute myeloid leukemia.
Expert review of hematology - 1 Oct 2012
Walker Alison, Marcucci Guido
Abstract excerpt
Chromosomal abnormalities are detected in 50-60% of patients with acute myeloid leukemia (AML) and are important predictors of prognosis and risk of relapse. The remaining patients, those with cytogenetically normal AML, are a seemingly homogeneous group that in fact consists of subsets of patients with distinct clinical outcomes. This heterogeneity is likely related to acquired gene mutations, as well as altered...
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