Article

Prognosis and treatment in acute myeloid leukemia: a comprehensive review

2024-08-06

Abstract excerpt

Abstract Acute myeloid leukemia (AML) is a heterogeneous disorder that is characterized by clonal expansion of immature "blast cells" in the bone marrow and peripheral circulation, resulting in bone marrow failure and inefficient erythropoiesis. The identification of numerous recurrent genetic mutations such as NPM1, CEBPA, and FLT3-ITD has stratified AML into favorable, intermediate, and adverse-risk groups, resp...

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Literature Corpus work: 0ff5c349-6cb8-50fe-950c-2ae7cd780e54
DOI: 10.1186/s43042-024-00563-w

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