Association study of LMP gene polymorphisms in Mexican patients with spondyloarthritis.

doi:10.1016/j.humimm.2004.09.007

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Article

Association study of LMP gene polymorphisms in Mexican patients with spondyloarthritis.

Human immunology - 1 Dec 2004

Vargas-Alarcón Gilberto, Gamboa Ricardo, Zuñiga Joaquín, Fragoso José Manuel, Hernández-Pacheco Guadalupe, Londoño John, Pacheco-Tena Cesar, Cardiel Mario H, Granados Julio, Burgos-Vargas Rubén

Abstract excerpt

To evaluate the role of LMP (low molecular weight protein) genes as susceptibility markers for spondyloarthritis (SpA), LMP gene polymorphisms were analyzed in 223 Mexican patients with SpA (81 undifferentiated SpA [U-SpA], 117 with ankylosing spondylitis [AS], 25 with reactive arthritis) and in 139 ethnically matched healthy individuals. LMP genotypes were determined by polymerase chain reaction-restriction...

Topics

Adolescent
Adult
Alleles
Arthritis, Reactive
Base Sequence
Case-Control Studies
Cysteine Endopeptidases
DNA
Female
Gene Frequency
HLA-B27 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Mexico

Multienzyme Complexes

Polymorphism, Genetic

Proteasome Endopeptidase Complex

Spondylarthropathies

Source

Open in PubMed

Identifiers

PMID: 15603870
DOI: 10.1016/j.humimm.2004.09.007

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