Polymorphism in the LMP2 gene influences the relative risk for acute anterior uveitis in unselected patients with ankylosing spondylitis.

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Article

Polymorphism in the LMP2 gene influences the relative risk for acute anterior uveitis in unselected patients with ankylosing spondylitis.

Clinical and investigative medicine. Medecine clinique et experimentale - 1 Feb 1995

Maksymowych W P, Russell A S

Abstract excerpt

Although human leukocyte antigen (HLA) B27 has been directly implicated in the pathogenesis of ankylosing spondylitis (AS), additional evidence favours the involvement of an additional genetic factor(s). In a previous population analysis of AS patients selected for a history of acute anterior uveitis (AAU), we had demonstrated a phenotypic association between polymorphism in an HLA-linked proteasome subunit gene,...

Topics

Adult
Aged
Cysteine Endopeptidases
Endopeptidases
Female
Genetic Heterogeneity
Genotype
Homozygote
Humans
Major Histocompatibility Complex
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Phenotype

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Risk

Spondylitis, Ankylosing

Uveitis, Anterior

Source

Open in PubMed

Identifiers

PMID: 7768065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7768065-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Polymorphism in the LMP2 gene influences the relative risk for acute anterior uveitis in unselected patients with ankylosing spondylitis.PMID 7768065Read ↗

Polymorphism in the LMP2 gene influences susceptibility to extraspinal disease in HLA-B27 positive individuals with ankylosing spondylitis.Semantic proximity Read ↗

The LMP2 CfoI polymorphism is associated with ankylosing spondylitis (AS) risk but not with acute anterior uveitis (AAU): A meta-analysis.Semantic proximity Read ↗

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LMP2 polymorphism is associated with extraspinal disease in HLA-B27 negative Caucasian and Mexican Mestizo patients with ankylosing spondylitis.Semantic proximity Read ↗

Polymorphism of the LMP2 gene and disease phenotype in ankylosing spondylitis: no association with disease severity.Semantic proximity Read ↗

Polymorphism in an HLA linked proteasome gene influences phenotypic expression of disease in HLA-B27 positive individuals.Semantic proximity Read ↗

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Analysis of the MHC class II encoded components of the HLA class I antigen processing pathway in ankylosing spondylitis.Semantic proximity Read ↗

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