Article
Effect of HLA-B and HLA-DR genes on susceptibility to and severity of spondyloarthropathies in Mexican patients.
Annals of the rheumatic diseases - 1 Aug 2002
Vargas-Alarcón G, Londoño J D, Hernández-Pacheco G, Pacheco-Tena C, Castillo E, Cardiel M H, Granados J, Burgos-Vargas R
Abstract excerpt
OBJECTIVE: To investigate the role of HLA-B and HLA-DR genes as contributors to genetic susceptibility and clinical expression of the spondyloarthropathies (SpA) in the Mexican population. METHODS: The study included 172 patients with SpA (undifferentiated SpA 83, ankylosing spondylitis (AS) 64, and reactive arthritis 25) and 99 healthy controls. The HLA-B and HLA-DR alleles were detected by the polymerase chain...
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