Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism in an HLA linked proteasome gene influences phenotypic expression of disease in HLA-B27 positive individuals.

The Journal of rheumatology - 1 Apr 1994

Maksymowych W P, Wessler A, Schmitt-Egenolf M, Suarez-Almazor M, Ritzel G, Von Borstel R C, Pazderka F, Russell A S

Abstract excerpt

OBJECTIVE: To investigate the potential influence of the HLA-linked LMP (low molecular weight polypeptide) genes on disease susceptibility in HLA-B27 individuals with ankylosing spondylitis (AS). METHODS: A polymorphic CfoI restriction enzyme site in the coding region of one proteasome gene was evaluated in 125 genomic DNA samples from B27 individuals with well documented AS, 55 of whom had had acute iritis, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Amino Acid Sequence

Share to Base Sequence

Share to DNA Primers

Share to Genetic Linkage

Share to Homozygote

Share to Molecular Sequence Data

Source

Identifiers

PMID: 8035391

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism in an HLA linked proteasome gene influences phenotypic expression of disease in HLA-B27 positive individuals.PMID 8035391Read ↗

Polymorphism in the LMP2 gene influences disease susceptibility and severity in HLA-B27 associated juvenile rheumatoid arthritis.Semantic proximity Read ↗

Polymorphism in the LMP2 gene influences susceptibility to extraspinal disease in HLA-B27 positive individuals with ankylosing spondylitis.Semantic proximity Read ↗

HLA-B27 and genetic predisposing factors in spondyloarthropathies.Semantic proximity Read ↗

LMP2 polymorphism is associated with extraspinal disease in HLA-B27 negative Caucasian and Mexican Mestizo patients with ankylosing spondylitis.Semantic proximity Read ↗

Polymorphism in the LMP2 gene influences the relative risk for acute anterior uveitis in unselected patients with ankylosing spondylitis.Semantic proximity Read ↗

Association to HLA-DRB1∗08, HLA-DPB1∗0301 and homozygosity for an HLA-linked proteasome gene in juvenile ankylosing spondylitisSemantic proximity Read ↗

Association study of LMP gene polymorphisms in Mexican patients with spondyloarthritis.Semantic proximity Read ↗

Analysis of the MHC class II encoded components of the HLA class I antigen processing pathway in ankylosing spondylitis.Semantic proximity Read ↗

[Allelic polymorphism of genes encoding catalytic immunoproteasome subunits and its functional meaning].Semantic proximity Read ↗

HLA-DRB1*08 influences the development of disease in Mexican Mestizo with spondyloarthropathy.Semantic proximity Read ↗

Polymorphism in the MHC-encoded LMP7 gene: association with JRA without functional significance for immunoproteasome assembly.Semantic proximity Read ↗

Allelic variation at the TAP 1 locus influences disease phenotype in HLA-B27 positive individuals with ankylosing spondylitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.