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Article

Polymorphism in the LMP2 gene influences susceptibility to extraspinal disease in HLA-B27 positive individuals with ankylosing spondylitis.

Annals of the rheumatic diseases - 1 Apr 1995

Maksymowych W P, Suarez-Almazor M, Chou C T, Russell A S

Abstract excerpt

OBJECTIVE: To investigate the potential influence of the HLA-linked LMP2 gene on disease susceptibility in HLA-B27 individuals with ankylosing spondylitis (AS). METHODS: A polymorphic CfoI restriction enzyme site in the coding region of the LMP2 gene was evaluated in genomic DNA samples from 193...

Topics

Adult
Aged
Arthritis
Base Sequence
China
Cysteine Endopeptidases
Female
Genetic Predisposition to Disease
HLA-B27 Antigen
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Polymorphism, Genetic

Proteins

Spondylitis, Ankylosing

Source

Open in PubMed Open full text

Identifiers

PMID: 7763114
DOI: 10.1136/ard.54.4.321
PMCID: PMC1005583

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7763114-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Polymorphism in the LMP2 gene influences susceptibility to extraspinal disease in HLA-B27 positive individuals with ankylosing spondylitis.PMID 7763114Read ↗

LMP2 polymorphism is associated with extraspinal disease in HLA-B27 negative Caucasian and Mexican Mestizo patients with ankylosing spondylitis.Semantic proximity Read ↗

Polymorphism in the LMP2 gene influences disease susceptibility and severity in HLA-B27 associated juvenile rheumatoid arthritis.Semantic proximity Read ↗

The LMP2 CfoI polymorphism is associated with ankylosing spondylitis (AS) risk but not with acute anterior uveitis (AAU): A meta-analysis.Semantic proximity Read ↗

[The relationship between polymorphism of LMP2 and LMP7 genes and the phenotype of ankylosing spondylitis].Semantic proximity Read ↗

Polymorphism in an HLA linked proteasome gene influences phenotypic expression of disease in HLA-B27 positive individuals.Semantic proximity Read ↗

Polymorphism in the LMP2 gene influences the relative risk for acute anterior uveitis in unselected patients with ankylosing spondylitis.Semantic proximity Read ↗

Association study of LMP gene polymorphisms in Mexican patients with spondyloarthritis.Semantic proximity Read ↗

Polymorphism of the LMP2 gene and disease phenotype in ankylosing spondylitis: no association with disease severity.Semantic proximity Read ↗

Analysis of the MHC class II encoded components of the HLA class I antigen processing pathway in ankylosing spondylitis.Semantic proximity Read ↗

HLA-DRB1*08 influences the development of disease in Mexican Mestizo with spondyloarthropathy.Semantic proximity Read ↗

Radiographic severity of ankylosing spondylitis is associated with polymorphism of the large multifunctional peptidase 2 gene in the Spondyloarthritis Research Consortium of Canada cohort.Semantic proximity Read ↗

Major histocompatility complex haplotypic associations in Felty's syndrome and large granular lymphocyte syndrome are secondary to allelic association with HLA-DRB1 *0401.Semantic proximity Read ↗

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