Article
Microarray gene expression analysis of the Fob3b obesity QTL identifies positional candidate gene Sqle and perturbed cholesterol and glycolysis pathways.
Physiological genomics - 10 Feb 2005
Stylianou Ioannis M, Clinton Michael, Keightley Peter D, Pritchard Clare, Tymowska-Lalanne Zuzzana, Bünger Lutz, Horvat Simon
Abstract excerpt
Obesity-related diseases are poised to become the primary cause of death in developed nations. While a number of monogenic causes of obesity have recently been identified, these are responsible for only a small proportion of human cases of obesity. Quantitative trait locus (QTL) studies using animal models have revealed hundreds of potential loci that affect obesity; however, few have been further analyzed beyond...
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