Article
Fine-mapping gene-by-diet interactions on chromosome 13 in a LG/J x SM/J murine model of obesity.
Diabetes - 1 Jun 2005
Ehrich Thomas H, Hrbek Tomas, Kenney-Hunt Jane P, Pletscher L Susan, Wang Bing, Semenkovich Clay F, Cheverud James M
Abstract excerpt
Obesity is one of the most serious threats to human health today. Although there is general agreement that environmental factors such as diet have largely caused the current obesity pandemic, the environmental changes have not affected all individuals equally. To model gene-by-environment interactions in a mouse model system, our group has generated an F(16) advanced intercross line (AIL) from the SM/J and LG/J...
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