Article

QTL-mapping in the obese Berlin Fat Mouse identifies additional candidate genes for obesity and fatty liver disease

2022-03-11

Abstract excerpt

<h4>Background: </h4> The Berlin Fat Mouse Inbred line (BFMI) is a model for obesity and the metabolic syndrome. This study aimed to identify genetic variants associated with liver weight, liver triglycerides, and body weight using the obese BFMI sub-line BFMI861-S1. BFMI861-S1 mice are insulin resistant and store ectopic fat in the liver. Methods In generation 10, 58 males and 65 females of the advanced intercro...

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Literature Corpus work: 445bf159-7fcb-528e-8ae9-62172132e8fe
DOI: 10.21203/rs.3.rs-1339100/v1

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