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Article

A Stratified Transcriptomics Analysis of Polygenic Fat and Lean Mouse Adipose Tissues Identifies Novel Candidate Obesity Genes

7 Sept 2011

Abstract excerpt

BACKGROUND: Obesity and metabolic syndrome results from a complex interaction between genetic and environmental factors. In addition to brain-regulated processes, recent genome wide association studies have indicated that genes highly expressed in adipose tissue affect the distribution and function of fat and thus contribute to obesity. Using a stratified transcriptome gene enrichment approach we attempted to...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Share to Cardiovascular Disease and Adiposity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21915269
DOI: 10.1371/journal.pone.0023944

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