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Article

Conditional cytomegalovirus replication in vitro and in vivo.

Journal of virology - 1 Jan 2005

Rupp Brigitte, Ruzsics Zsolt, Sacher Torsten, Koszinowski Ulrich H

Abstract excerpt

We have established a conditional gene expression system for cytomegalovirus which allows regulation of genes independently from the viral replication program. Due to the combination of all elements required for regulated expression in the same viral genome, conditional viruses can be studied in different cell lines in vitro and in the natural host in vivo. The combination of a self-sufficient...

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Identifiers

PMID: 15596841
DOI: 10.1128/JVI.79.1.486-494.2005
PMCID: PMC538716

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Source receipt: pubmed, retrieved 7 Sept 2026.

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