Article
Investigation of murine cytomegalovirus latency and reactivation in mice using viral mutants and the polymerase chain reaction.
Journal of medical virology - 1 Apr 1996
Bevan I S, Sammons C C, Sweet C
Abstract excerpt
Studies with 6 ts mutants of mouse cytomegalovirus indicated that mutants tsm1, tsm2, tsm3, and tsm6, like wild-type (wt) virus, produced acute infection in mice, became latent, and were reactivated as infectious virus immunosuppression. Using PCR, all five viruses expressed immediate-early (IE)-1, early (E)-1, and late (L, gB) genes during acute infection in all tissues examined (salivary glands, lung, spleen,...
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