Article
A shift in the balance of inhibitory and activating Fcgamma receptors on monocytes toward the inhibitory Fcgamma receptor IIb is associated with prevention of monocyte activation in rheumatoid arthritis.
Arthritis and rheumatism - 1 Dec 2004
Wijngaarden Siska, van de Winkel Jan G J, Jacobs Kim M G, Bijlsma Johannes W J, Lafeber Floris P J G, van Roon Joel A G
Abstract excerpt
OBJECTIVE: To assess surface expression of the inhibitory receptor for IgG (Fcgamma receptor IIb [FcgammaRIIb]) in relation to activating FcgammaR on monocyte/macrophages from patients with rheumatoid arthritis (RA) and healthy controls and to study the influence of proinflammatory and antiinflammatory cytokines on the balance of inhibitory and activating FcgammaR. METHODS: Using a combination of genotyping and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.