Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2007

Su Kaihong, Yang Hengxuan, Li Xinrui, Li Xiaoli, Gibson Andrew W, Cafardi John M, Zhou Tong, Edberg Jeffrey C, Kimberly Robert P

Abstract excerpt

FcgammaRIIb (CD32B, Online Mendelian Inheritance in Man 604590), an IgG FcR with a tyrosine-based inhibitory motif, plays a critical role in the balance of tolerance and autoimmunity in murine models. However, the high degree of homology between FcgammaRIIb and FcgammaRIIa in humans and the lack of specific Abs to differentiate them have hampered study of the normal expression profile of FcgammaRIIb and its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Leukocytes

Share to Lupus Erythematosus, Systemic

Share to Promoter Regions, Genetic

Share to Receptors, IgG

Source

Open in PubMed Open full text

Identifiers

PMID: 17312177
DOI: 10.4049/jimmunol.178.5.3272
PMCID: PMC2824439

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus.PMID 17312177Read ↗

A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. I. Regulatory FCGR2B polymorphisms and their association with systemic lupus erythematosus.Semantic proximity Read ↗

FcγRIIB, FcγRIIIB, and systemic lupus erythematosusSemantic proximity Read ↗

FcgammaR polymorphisms: Implications for function, disease susceptibility and immunotherapy.Semantic proximity Read ↗

Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria.Semantic proximity Read ↗

The functional variant of the inhibitory Fcgamma receptor IIb (CD32B) is associated with the rate of radiologic joint damage and dendritic cell function in rheumatoid arthritis.Semantic proximity Read ↗

A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. II. Differential binding of GATA4 and Yin-Yang1 transcription factors and correlated receptor expression and function.Semantic proximity Read ↗

FcγRIIB as a modulator of autoimmune disease susceptibilitySemantic proximity Read ↗

Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus.Semantic proximity Read ↗

FcgammaRIIB in autoimmunity and infection: evolutionary and therapeutic implications.Semantic proximity Read ↗

Fcgamma receptors: structure, function and role as genetic risk factors in SLE.Semantic proximity Read ↗

Receptors for immunoglobulin G. Molecular diversity and implications for disease.Semantic proximity Read ↗

A Comprehensive Review of Fc Gamma Receptors and Their Role in SLESemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.