Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel subset of NK cells expressing high levels of inhibitory FcgammaRIIB modulating antibody-dependent function.

Journal of leukocyte biology - 1 Dec 2008

Dutertre Charles-Antoine, Bonnin-Gélizé Emmanuelle, Pulford Karen, Bourel Dominique, Fridman Wolf-Herman, Teillaud Jean-Luc

Abstract excerpt

NK cells can kill antibody-coated target cells following engagement of FcgammaRIIIA, the major activating FcgammaR expressed by these cells. The presence of FcgammaRIIC (CD32C) has also been reported, but its contribution to the FcgammaR-dependent effector functions of NK cells remains debated. We demonstrate here that inhibitory FcgammaRIIB is also expressed by a small subset of CD56+/NKp46+ NK cells and can...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Cell Culture Techniques

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique

Share to Immunoglobulin G

Share to Immunoprecipitation

Share to Killer Cells, Natural

Share to Lymphocyte Subsets

Share to Receptors, IgG

Source

Identifiers

PMID: 18719017
DOI: 10.1189/jlb.0608343

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel subset of NK cells expressing high levels of inhibitory FcgammaRIIB modulating antibody-dependent function.PMID 18719017Read ↗

FcγRIIB as a modulator of autoimmune disease susceptibilitySemantic proximity Read ↗

Cutting Edge: Antibody-Dependent Memory-like NK Cells Distinguished by FcRγ DeficiencySemantic proximity Read ↗

Natural killer cell division regulates FcεRIγ expression downstream of mTOR activitySemantic proximity Read ↗

Functional CD32 molecules on human NK cells.Semantic proximity Read ↗

A subset of CD16-natural killer cells without antibody-dependent cellular cytotoxicity function.Semantic proximity Read ↗

Allelic polymorphisms in the FcgammaRIIC gene can influence its function on normal human natural killer cells.Semantic proximity Read ↗

Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression.Semantic proximity Read ↗

Assessment of Human Natural Killer Cell Events Driven by FcγRIIIa Engagement in the Presence of Therapeutic Antibodies.Semantic proximity Read ↗

FcgammaR polymorphisms: Implications for function, disease susceptibility and immunotherapy.Semantic proximity Read ↗

IgG Fc ReceptorsSemantic proximity Read ↗

A Comprehensive Review of Fc Gamma Receptors and Their Role in SLESemantic proximity Read ↗

CD94 functions as a natural killer cell inhibitory receptor for different HLA class I alleles: identification of the inhibitory form of CD94 by the use of novel monoclonal antibodies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.