Article
Immunoglobulin G fc-receptor (FcgammaR) IIA, IIIA, and IIIB polymorphisms related to disease severity in rheumatoid arthritis.
The Journal of rheumatology - 1 Jun 2002
Brun Johan G, Madland Tor M, Vedeler Christian A
Abstract excerpt
OBJECTIVE: Fc receptors for IgG (FcyR) modulate immune responses. FcyR are expressed on various leukocytes and contain allelic polymorphisms with different capacity for IgG binding and phagocytosis. We investigated the distribution of FcgammaRIIA, FcgammaRIIIA, and FcgammaRIIIB polymorphisms in rheumatoid arthritis (RA) and whether they were related to disease expression and severity. METHODS: Ninety-six controls...
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