Article
Fc gamma R expression on NK cells influences disease severity in rheumatoid arthritis.
Genes and immunity - 1 Nov 2004
Stewart-Akers A M, Cunningham A, Wasko M C, Morel P A
Abstract excerpt
Rheumatoid arthritis (RA) is associated with autoantibodies, the best known of which is rheumatoid factor (RF). RF/IgG complexes interact with FcgammaR on the surface of neutrophils, NK cells and monocyte/macrophages. We have analyzed the expression pattern and allelic polymorphisms of three FcgammaR genes (FcgammaRIIA, FcgammaRIIC and FcgammaRIIIA) in a large sample of RA patients and normal donors. We have...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
