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Article

Association of a functional CD19 polymorphism with susceptibility to systemic sclerosis.

Arthritis and rheumatism - 1 Dec 2004

Tsuchiya Naoyuki, Kuroki Kimiko, Fujimoto Manabu, Murakami Yoshinori, Tedder Thomas F, Tokunaga Katsushi, Takehara Kazuhiko, Sato Shinichi

Abstract excerpt

OBJECTIVE: CD19 is overexpressed in B cells from patients with systemic sclerosis (SSc), and plays a crucial role not only for autoantibody production, but also for skin fibrosis in mouse models. We previously reported the association of a GT repeat polymorphism in the 3'-untranslated region (3'-UTR) of CD19 with human systemic lupus erythematosus. In this study, we examined whether CD19 polymorphisms are...

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Share to Antigens, CD19
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

Share to Polymorphism, Single-Stranded Conformational

Share to Scleroderma, Systemic

Source

Identifiers

PMID: 15593213
DOI: 10.1002/art.20674

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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