Article
Association of BCL2 polymorphisms and the IL19 single nucleotide polymorphism rs2243188 with systemic lupus erythematosus.
The Journal of international medical research - 1 May 2021
Wang Weijie, Wang Xinchang, Yang Kepeng, Fan Yongsheng
Abstract excerpt
OBJECTIVE: Abnormal B cell lymphoma-2 (Bcl-2) and interleukin-19 (IL-19) expression is closely related to systemic lupus erythematosus (SLE) pathogenesis. We aimed to determine whether BCL2 polymorphisms and a single nucleotide polymorphism (SNP) of IL19 are significantly associated with SLE susceptibility and if this is affected by synergism between IL19 and BCL2 genotypes. METHODS: This observational cohort...
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