Article

A Family Screening of CD19 Gene Mutation by Restriction Fragment Length Polymorphism

2021-10-31

Abstract excerpt

<h4>Background: </h4> CD19 molecule found on B lymphocyte surface forms CD19 complex together with CD21, CD81, CD225 in mature B cells and regulates B lymphocyte activation with antigen stimulation. Mutation(s) in the gene encoding the CD19 molecule affect CD19 protein expression and primary immunodeficiency (PID) occurs. Some genetic method, especially sanger and next generation sequencing and flow cytometric met...

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Literature Corpus work: ee823a76-80b3-5b1e-8c48-03edaa4c945a
DOI: 10.22541/au.163570275.56925926/v1

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