Article

Inherited CD19 deficiency impairs signaling in plasma cells

2022-03-31

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The human CD19 antigen is expressed throughout B cell ontogeny with the exception of neoplastic plasma cells and a subset of normal plasma cells. CD19 plays a role in propagating signals from the B cell receptor and other receptors such as CXCR4 in mature B cells. Studies of CD19-deficient patients have confirmed its function during the initial stages of B cell...

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Literature Corpus work: bba4b410-8b33-5919-97de-0ff16c6ecdad
DOI: 10.21203/rs.3.rs-1498757/v1

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