Article
Heterogeneity testing in meta-analysis of genome searches.
Genetic epidemiology - 1 Feb 2005
Zintzaras Elias, Ioannidis John P A
Abstract excerpt
Genome searches for identifying susceptibility loci for the same complex disease often give inconclusive or inconsistent results. Genome Search Meta-analysis (GSMA) is an established non-parametric method to identify genetic regions that rank high on average in terms of linkage statistics (e.g., lod scores) across studies. Meta-analysis typically aims not only to obtain average estimates, but also to quantify...
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