Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identifying systematic heterogeneity patterns in genetic association meta-analysis studies.

PLoS genetics - 1 May 2017

Magosi Lerato E, Goel Anuj, Hopewell Jemma C, Farrall Martin

Abstract excerpt

Progress in mapping loci associated with common complex diseases or quantitative inherited traits has been expedited by large-scale meta-analyses combining information across multiple studies, assembled through collaborative networks of researchers. Participating studies will usually have been independently designed and implemented in unique settings that are potential sources of phenotype, ancestry or other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Artery Disease
Share to Genetic Heterogeneity
Share to Genome, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Genotype

Share to Meta-Analysis as Topic

Share to Phenotype

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 28459806
DOI: 10.1371/journal.pgen.1006755
PMCID: PMC5432194

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identifying systematic heterogeneity patterns in genetic association meta-analysis studies.PMID 28459806Read ↗

An evaluation of different meta-analysis approaches in the presence of allelic heterogeneity.Semantic proximity Read ↗

Meta-analysis of genetic association studies under heterogeneity.Semantic proximity Read ↗

Genetic heterogeneity: Challenges, impacts, and methods through an associative lens.Semantic proximity Read ↗

Meta-analysis of sequencing studies with heterogeneous genetic associations.Semantic proximity Read ↗

Exploring the Major Sources and Extent of Heterogeneity in a Genome-Wide Association Meta-Analysis.Semantic proximity Read ↗

Meta-analysis methods for genome-wide association studies and beyond.Semantic proximity Read ↗

Meta-analysis of gene-level tests for rare variant association.Semantic proximity Read ↗

Methods for meta-analysis of genetic data.Semantic proximity Read ↗

Replication validity of genetic association studies.Semantic proximity Read ↗

Meta-Analysis of Common and Rare Variants.Semantic proximity Read ↗

General framework for meta-analysis of rare variants in sequencing association studies.Semantic proximity Read ↗

Required sample size and nonreplicability thresholds for heterogeneous genetic associations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.