Article
Genetics of endometrial cancer.
Familial cancer - 1 Sept 2014
Shai Ayelet, Segev Yakir, Narod Steven A
Abstract excerpt
Women who report a history of endometrial cancer in a first-degree relative are at increased risk of endometrial cancer, with a hazard ratio of 1.5 to 2.0. Only a minority of patients with familial endometrial cancer have a recognized cancer syndrome. Lynch syndrome is the most common genetic syndrome associated with endometrial cancer and a marked increased risk of colon cancer. Cowden syndrome is a rare...
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