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Article

Genetics of Cowden syndrome: through the looking glass of oncology.

International journal of oncology - 1 Mar 1998

Eng C

Abstract excerpt

Cowden syndrome (CS) is an autosomal dominant inherited syndrome characterised by hamartoma development in multiple organs and a risk of breast, thyroid and other cancers. The susceptibility gene for this syndrome was mapped to 10q22-23. Subsequently, germline mutations in PTEN, which encodes a d...

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Source

Identifiers

PMID: 9472113
DOI: 10.3892/ijo.12.3.701

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9472113-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Genetics of Cowden syndrome: through the looking glass of oncology.PMID 9472113Read ↗

Cowden syndrome: recognizing and managing a not-so-rare hereditary cancer syndrome.Semantic proximity Read ↗

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Breast cancer risk and clinical implications for germline PTEN mutation carriers.Semantic proximity Read ↗

Second malignant neoplasms in patients with Cowden syndrome with underlying germline PTEN mutations.Semantic proximity Read ↗

Cancer and Lhermitte-Duclos disease are common in Cowden syndrome patientsSemantic proximity Read ↗

Germline PIK3CA and AKT1 mutations in Cowden and Cowden-like syndromes.Semantic proximity Read ↗

KLLN epigenotype-phenotype associations in Cowden syndrome.Semantic proximity Read ↗

Male breast cancer in Cowden syndrome patients with germline PTEN mutations.Semantic proximity Read ↗

Cowden syndrome.Semantic proximity Read ↗

Unexpected cancer-predisposition gene variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome patients without underlying germline PTEN mutations.Semantic proximity Read ↗

PTEN hamartoma tumor syndrome: clinical risk assessment and management protocol.Semantic proximity Read ↗

Cowden Syndrome: A Critical Review of the Clinical LiteratureSemantic proximity Read ↗

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