Article
Molecular genetic characterization of tamoxifen-associated endometrial cancer.
Gynecologic oncology - 1 Jan 2005
Prasad Monica, Wang Hong, Douglas Wayne, Barakat Richard R, Ellenson Lora Hedrick
Abstract excerpt
OBJECTIVES: The non-steroidal, selective estrogen receptor modulator tamoxifen is currently the most extensively used hormonal agent for the prevention and treatment of estrogen receptor-positive breast cancer. Epidemiologic studies and clinical trials have shown an increased risk of endometrial cancer with tamoxifen exposure; however, few studies have examined these tumors on a molecular level. We sought to...
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