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Article

A short conserved motif in ALYREF directs cap- and EJC-dependent assembly of export complexes on spliced mRNAs.

Nucleic acids research - 18 Mar 2016

Gromadzka Agnieszka M, Steckelberg Anna-Lena, Singh Kusum K, Hofmann Kay, Gehring Niels H

Abstract excerpt

The export of messenger RNAs (mRNAs) is the final of several nuclear posttranscriptional steps of gene expression. The formation of export-competent mRNPs involves the recruitment of export factors that are assumed to facilitate transport of the mature mRNAs. Using in vitro splicing assays, we show that a core set of export factors, including ALYREF, UAP56 and DDX39, readily associate with the spliced RNAs in an...

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Identifiers

PMID: 26773052
DOI: 10.1093/nar/gkw009
PMCID: PMC4797287

Genes

ALYREF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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