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Article

Phenotypic and genotypic characterization of the Indiana University rat lines selectively bred for high and low alcohol preference.

Behavior genetics - 1 Sept 2002

Murphy James M, Stewart Robert B, Bell Richard L, Badia-Elder Nancy E, Carr Lucinda G, McBride William J, Lumeng Lawrence, Li Ting-Kai

Abstract excerpt

The Indiana lines of selected rats, the HAD and LAD replicates and the P and NP lines, were bred for high and low alcohol preference. The P and HAD lines have met criteria for an animal model of alcoholism in that they voluntarily consume sufficient ethanol to achieve significant blood alcohol concentrations, and their alcohol-seeking behavior is reinforced by the pharmacological effects of ethanol rather than...

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Source

Identifiers

PMID: 12405517
DOI: 10.1023/a:1020266306135

Genes

LAD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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