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Article

Selective breeding for high and low alcohol preference in mice.

Behavior genetics - 1 Jan 1999

Grahame N J, Li T K, Lumeng L

Abstract excerpt

High and low alcohol preference (HAP and LAP, respectively) mice were created by 10 generations of bidirectional selection for differences in two-bottle choice alcohol consumption. The progenitors used for selection were HS/lbg mice, which are a genetically defined, outbred stock. During selection, mice had 24-h, daily access to 10% alcohol (v/v) and water ad libitum for 30 days and were selected based on the...

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PMID: 10371758
DOI: 10.1023/a:1021489922751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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