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Article

Wnt4 is required for proper male as well as female sexual development.

Developmental biology - 15 Dec 2004

Jeays-Ward Katherine, Dandonneau Mathieu, Swain Amanda

Abstract excerpt

Genes previously implicated in mammalian sexual development have either a male- or female-specific role. The signaling molecule WNT4 has been shown to be important in female sexual development. Lack of Wnt4 gives rise to masculinization of the XX gonad and we showed previously that the role of WNT4 was to inhibit endothelial and steroidogenic cell migration into the developing ovary. Here we show that Wnt4 also...

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Source

Identifiers

PMID: 15581876
DOI: 10.1016/j.ydbio.2004.08.049

Genes

WNT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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