Article
Interleukin-8 in whole blood and clinical status in cystic fibrosis.
Cytokine - 7 Jan 2005
Schmitt-Grohé Sabina, Naujoks Christian, Bargon Joachim, Wagner Thomas O, Schubert Ralf, Hippe Valerie, Zielen Stefan
Abstract excerpt
Cytokines and polymorphonuclear leukocytes play a key role in immune mediated inflammation in progressive pulmonary damage due to cystic fibrosis. The aim of this study is to establish a simple measure of the host's propensity to secrete inflammatory cytokines and to correlate this with clinical status. Patients (n=44, median age 16 years) with the DeltaF 508 mutation (homozygous) were grouped according to their...
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