Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modulation of cystic fibrosis lung disease by variants in interleukin-8.

Genes and immunity - 1 Sept 2008

Hillian A D, Londono D, Dunn J M, Goddard K A B, Pace R G, Knowles M R, Drumm M L

Abstract excerpt

Cystic fibrosis pulmonary disease is characterized by excessive and prolonged inflammation. CF Pulmonary disease severity exhibits considerable variation that, to some extent, appears to be due to the presence of modifier genes. Several components of the inflammatory response are known to have altered regulation in the CF lung. Genetic variants in 52 inflammatory genes were tested for associations with lung...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cystic Fibrosis
Share to Cystic Fibrosis Research Advances
Share to Interleukin-8

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Share to Neonatal Respiratory Health Research

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Sex Characteristics

Source

Open in PubMed Open full text

Identifiers

PMID: 18563170
DOI: 10.1038/gene.2008.42
PMCID: PMC4255265

Genes

CXCL6
RASSF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modulation of cystic fibrosis lung disease by variants in interleukin-8.PMID 18563170Read ↗

Genetic variations in inflammatory mediators influence lung disease progression in cystic fibrosis.Semantic proximity Read ↗

IL8 gene as modifier of cystic fibrosis: unraveling the factors which influence clinical variability.Semantic proximity Read ↗

Cytokine gene polymorphisms and severity of CF lung disease.Semantic proximity Read ↗

Update on gene modifiers in cystic fibrosisSemantic proximity Read ↗

Variants in the interleukin 8 gene and the response to inhaled bronchodilators in cystic fibrosis.Semantic proximity Read ↗

Current evidence on the effect of highly effective CFTR modulation on interleukin-8 in cystic fibrosis.Semantic proximity Read ↗

Modifier genes in cystic fibrosis lung disease.Semantic proximity Read ↗

IL1B polymorphisms modulate cystic fibrosis lung disease.Semantic proximity Read ↗

Systemic inflammatory mediators and cystic fibrosis genotype.Semantic proximity Read ↗

Disease modifying genes in cystic fibrosis.Semantic proximity Read ↗

Cystic fibrosis, disease severity, and a macrophage migration inhibitory factor polymorphism.Semantic proximity Read ↗

IL1B gene variants, but not TNF, CXCL8, IL6 and IL10, modify the course of cystic fibrosis in Polish patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.