Article
Variants in the interleukin 8 gene and the response to inhaled bronchodilators in cystic fibrosis.
Jornal de pediatria - 1 Jan 2000
Furlan Larissa Lazzarini, Ribeiro José Dirceu, Bertuzzo Carmen Sílvia, Salomão Junior João Batista, Souza Dorotéia Rossi Silva, Marson Fernando Augusto Lima
Abstract excerpt
OBJECTIVE: Interleukin 8 protein promotes inflammatory responses, even in airways. The presence of interleukin 8 gene variants causes altered inflammatory responses and possibly varied responses to inhaled bronchodilators. Thus, this study analyzed the interleukin 8 variants (rs4073, rs2227306, and rs2227307) and their association with the response to inhaled bronchodilators in cystic fibrosis patients. METHODS:...
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