Article
Lipopolysaccharide binding protein, cytokine production in whole blood, and lipoproteins in cystic fibrosis.
Pediatric research - 1 Nov 2005
Schmitt-Grohé Sabina, Hippe Valerie, Igel Michael, von Bergmann Karl, Posselt Heinz G, Krahl Andreas, Smaczny Christina, Wagner Thomas O F, Nikolazik Wilfried, Schubert Ralf, Lentze Michael J, Zielen Stefan
Abstract excerpt
According to the endotoxin lipoprotein hypothesis, lipoproteins may down-regulate cytokine production by neutralizing lipopolysaccharide (LPS) binding protein (LBP) complexes. We investigated the correlation between lipoproteins, LBP, cytokine production, and clinical status in Delta F 508 (homozygous) individuals. Cystic fibrosis patients with mild disease were compared with those with more severe disease and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
