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Article

Polymorphisms in the interleukin-8 gene in patients with chronic obstructive pulmonary disease.

Electrophoresis - 1 Aug 2005

Arinir Umut, Klein Wolfram, Rohde Gernot, Stemmler Susanne, Epplen Joerg T, Schultze-Werninghaus Gerhard

Abstract excerpt

Airway inflammation is the main pathophysiological feature of patients with chronic obstructive pulmonary disease (COPD). Interleukin-8 (IL-8) is a potent chemoattractant for neutrophils and eosinophils. Increased IL-8 levels were observed in bronchoalveolar lavage (BAL) and induced sputum in patients with COPD. To evaluate the role of the IL-8 gene, we genotyped blood samples of 122 COPD-patients and 385 healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymerase Chain Reaction

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Share to Promoter Regions, Genetic

Share to Pulmonary Disease, Chronic Obstructive

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Source

Identifiers

PMID: 16007706
DOI: 10.1002/elps.200500095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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