Article
Hematotoxicity in workers exposed to low levels of benzene.
Science (New York, N.Y.) - 3 Dec 2004
Lan Qing, Zhang Luoping, Li Guilan, Vermeulen Roel, Weinberg Rona S, Dosemeci Mustafa, Rappaport Stephen M, Shen Min, Alter Blanche P, Wu Yongji, Kopp William, Waidyanatha Suramya, Rabkin Charles, Guo Weihong, Chanock Stephen, Hayes Richard B, Linet Martha, Kim Sungkyoon, Yin Songnian, Rothman Nathaniel, Smith Martyn T
Abstract excerpt
Benzene is known to have toxic effects on the blood and bone marrow, but its impact at levels below the U.S. occupational standard of 1 part per million (ppm) remains uncertain. In a study of 250 workers exposed to benzene, white blood cell and platelet counts were significantly lower than in 140 controls, even for exposure below 1 ppm in air. Progenitor cell colony formation significantly declined with...
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