Article
Functions and distribution of NQO1 in human bone marrow: potential clues to benzene toxicity.
Chemico-biological interactions - 30 May 2005
Ross David
Abstract excerpt
NADPH:quinone oxidoreductase 1 (NQO1) may perform multiple functions within the cell. It is known to detoxify benzene-derived quinones and generate antioxidant forms of ubiquinone and Vitamin E. Recently suggested roles for NQO1 which may have relevance for mechanisms underlying benzene toxicity include modulation of cellular redox balance, direct scavenging of superoxide, stabilization of p53 and stabilization...
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