Article
[Sensitivity comparison of DNA damage and repair capacity in TK6 and WTK1 cells].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 Nov 2004
Zhang Jian-qing, Zhang Li-shi, Wang Rui-shu
Abstract excerpt
OBJECTIVE: Explore the mechanisms of DNA damage and repair capacity in TK6 and WTK1 cells that are derived from the same parental cell line WI-L2 (tk+/+) human diploid lymphoblastoid cells but are different in their p53 gene status. METHODS: The TK6 and WTK1 cells treated with H2O2 were detected by single cell gel electrophoresis. Then a comparison was made on the comet cell rate, comet cell tail length and p53...
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