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DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death

18 Aug 2021

Abstract excerpt

The comet assay or single cell gel electrophoresis, is the most common method used to measure strand breaks and a variety of other DNA lesions in human populations. To estimate the risk of overall mortality, mortality by cause, and cancer incidence associated to DNA damage, a cohort of 2,403 healthy individuals (25,978 person-years) screened in 16 laboratories using the comet assay between 1996 and 2016 was...

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PMID: 34408182
DOI: 10.1038/s41598-021-95976-7

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