[Effects of pol beta on biological characteristics and DNA damage in mouse embryonic fibroblast].

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Article

[Effects of pol beta on biological characteristics and DNA damage in mouse embryonic fibroblast].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition - 1 May 2010

Luo Qing-Ying, Wu Mei, Liu Shu-Kun, Zhang Zun-Zhen

Abstract excerpt

OBJECTIVE: To explore the effect of DNA polymerase beta (pol beta) expression level on biological characteristics of mouse embryonic fibroblast (MEF) and the cellular response to DNA damage induced by potassium dichromate. METHODS: pol beta wild-type cells (pol beta +/+), pol beta null cells (pol beta -/-) and pol beta overexpressed cells (pol beta oe) were applied as a model system. The growth curve of cells was...

Topics

Animals
Cell Proliferation
Cells, Cultured
DNA Damage
DNA Polymerase beta
DNA Repair
Embryo, Mammalian
Fibroblasts
Mice
Mutation
Potassium Dichromate

Source

Open in PubMed

Identifiers

PMID: 20629302

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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