Article
[Comparison of TK gene mutation assay in TK6 and TK6-E6 cell induced by vinblastin and colcemid].
Wei sheng yan jiu = Journal of hygiene research - 1 Jul 2006
Wang Ya-nan, Shuai Pei-qiang, Ding Xiao-qin, Zhang Li-shi
Abstract excerpt
OBJECTIVE: To compare TK gene mutation assay in human lymphoblastoid cell lines TK6 and TK6-E6 induced by vinblastin and colcemid. METHODS: Regular TK gene mutation assays were experimented to detect cytotoxicity and mutation frequency at tk locus after TK6 and TK6-E6 human lymphoblastoid cells were treated with vinblastin and colcemid for 24h. RESULTS: Relative survival (RS%) and Relative suspension growth...
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