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Article

Altered p53 status correlates with differences in sensitivity to radiation-induced mutation and apoptosis in two closely related human lymphoblast lines.

Cancer research - 1 Jan 1995

Xia F, Wang X, Wang Y H, Tsang N M, Yandell D W, Kelsey K T, Liber H L

Abstract excerpt

Previous work identified TK6 and WTK1 as human lymphoblast cell lines from one donor that have different capacities to catalyze recombination and that vary significantly in their response to ionizing radiation. WTK1 cells are more resistant to the toxic effects of X-rays yet more sensitive to ind...

Topics

Apoptosis
Genes, p53
Humans
Mutation
RNA, Messenger
Tumor Cells, Cultured
Tumor Suppressor Protein p53

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7805021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7805021-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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