Article
[Thymidine kinase gene mutation assay--comparison of microwell method and soft agar method].
Wei sheng yan jiu = Journal of hygiene research - 1 May 2004
Shuai Peiqiang, Zhang Lishi, Wang Yijing
Abstract excerpt
OBJECTIVE: TK gene mutation assay was developed for a long time. Two methods are used in TK locus mutation assay, i.e. microwell method and soft agar method. Two methods were compared in this study so that to find out the better one to be used in China. METHODS: In this study, two methods (microwell method and soft agar method) were used for detecting and evaluating the mutagenesis of three positive mutagens,...
Topics
- Animals
- Leukemia L5178
- Mice
- Mutagenicity Tests
- Mutation
- Thymidine Kinase
- Tumor Cells, Cultured