Article
Factor VLeiden inhibits fibrinolysis in vivo.
Circulation - 7 Dec 2004
Parker Andrew C, Mundada Lakshmi V, Schmaier Alvin H, Fay William P
Abstract excerpt
BACKGROUND: Factor V(Leiden) (fV(Leiden)) predisposes to thrombosis by enhancing thrombin formation. This study tested the hypothesis that fV(Leiden) inhibits fibrinolysis in vivo. METHODS AND RESULTS: Radiolabeled clots were injected into the jugular veins of wild-type mice and mice heterozygous...
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