Article
Arterial thrombosis in mice with factor V Leiden mutation.
Vascular - 1 Jan 2000
Sampram Ellis S, Saad Yasser, Ouriel Kenneth
Abstract excerpt
The factor V Leiden (FVL) mutation has been demonstrated to be associated with the development of venous thrombosis in humans. Whether such a propensity also exists in the arterial circulation remains controversial. In an effort to minimize the variability that clouds the clinical study of arterial thrombosis, we studied FVL-associated arterial thrombosis in an experimental model of homozygous, heterozygous, and...
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