Article
Increased venous versus arterial thrombosis in the Factor V Leiden mouse.
Thrombosis research - 1 Jan 2007
Cooley Brian C, Chen Chao-Ying, Schmeling Gregory
Abstract excerpt
BACKGROUND: Deep vein thrombosis (DVT) occurs with high prevalence in association with the Factor V Leiden (R506Q) mutation, whereas most evidence suggests no correlation with clinical arterial thrombosis. OBJECTIVE: This study compared arterial to venous thrombosis in the mutationally analogous Factor V Leiden mouse. METHODS: Three separate vascular thrombosis models were evaluated in Fv(+/+) (wild-type),...
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