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Article

Genomic haplotype blocks may not accurately reflect spatial variation in historic recombination intensity.

Molecular biology and evolution - 1 Mar 2005

Verhoeven Koen J F, Simonsen Katy L

Abstract excerpt

Recently, genomic data have revealed a "block-like" structure of haplotype diversity on human chromosomes. This structure is anticipated to facilitate gene mapping studies, because strong associations among loci within a block may allow haplotype variation to be tagged with a limited number of markers. But its usefulness to mapping efforts depends on the consistency of the block structure within and among...

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PMID: 15563716
DOI: 10.1093/molbev/msi058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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