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Article

Demography, recombination hotspot intensity, and the block structure of linkage disequilibrium.

Current biology : CB - 8 Jan 2003

Stumpf Michael P H, Goldstein David B

Abstract excerpt

BACKGROUND: Effective gene mapping based on genetic association data will require detailed knowledge of patterns of linkage disequilibrium (LD) in human populations. It has been recently suggested that linkage disequilibrium in humans may be organized in a block-like structure, with islands of high LD separated by regions of rapid breakdown of LD due to recombination hotspots. The experimental data to date,...

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PMID: 12526738
DOI: 10.1016/s0960-9822(02)01404-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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